Sachin Daga
Krishna Institute of medical sciences, India.
Title: Early post operative infection after liver transplant – Indian perspective
Biography
Biography: Sachin Daga
Abstract
Infection occuring during early post operative period after liver transplantation result in significant rise in morbidity and mortality. Due to high immonusuppresive state immediately after liver transplant patients are prone for infections. During early period hospital acquired infection is most common cause of mortality after liver transplant. We have analysed our experence of 84 liver transplant performed during period of june 2012 to feb 2016. 54.8% of patient suffered from one or more episode of bacterial and /or fungal sepsisdurig their post operative hospitalisation. The median onset of infection was on day 4 after transplantation. In our experience Klebsiella was seen in 47.05%, acinetobacter – 29.41%, E coli 11.76%, Pseudomonas- 5.88%, and mucormycosis in 5.88%. Post operative infection was most ommon complication encounters after liver transplant. Among 84 Patients 46 developed infection. Out of 46 patient 14 died due to infection, off remaining two developed unusual infection. One developed gastric mucormycosis which was managed successfully with re=adical surgery. One patient developed malaria which improved with antimalarial.
In present series overall 1 year mortality was 28.57%(24 out of 84). Infection was most common cause of mortality was seen in 58.3% (14 out of 84), followed by small for size 12.5% (3 out of 24 ), cental pontine mylinolysis 12.5% (3 out of 24 ), bleeding 8.3% (2 out of 24 ) and portal vein thrombosis in 4.2% (1 out of 24).